The COX7A2L Antibody (Center) from MyBioSource.com is a Rabbit Polyclonal antibody to COX7A2L, and COX7RP. This antibody recognizes Human, and Mouse antigen. The COX7A2L Antibody (Center) has been validated for the following applications: ELISA, Immunohistochemistry, and Western Blot.
Description
Cytochrome c oxidase (COX), the terminal component of the
mitochondrial respiratory chain, catalyzes the electron transfer
from reduced cytochrome c to oxygen. This component is a
heteromeric complex consisting of 3 catalytic subunits encoded by
mitochondrial genes and multiple structural subunits encoded by
nuclear genes. The mitochondrially-encoded subunits function in
electron transfer, and the nuclear-encoded subunits may function in
the regulation and assembly of the complex. This nuclear gene
encodes a protein similar to polypeptides 1 and 2 of subunit VIIa
in the C-terminal region, and also highly similar to the mouse
Sig81 protein sequence. This gene is expressed in all tissues, and
upregulated in a breast cancer cell line after estrogen treatment.
It is possible that this gene represents a regulatory subunit of
COX and mediates the higher level of energy production in target
cells by estrogen